Wednesday, February 10, 2010

What substance can some types of fungi produce that is effective against some disease causing organisms?

For VCE BiologyWhat substance can some types of fungi produce that is effective against some disease causing organisms?
Antibiotics as Penicillium; a fungus produces the antibiotic penicillinWhat substance can some types of fungi produce that is effective against some disease causing organisms?
In 1941, penicillin from the fungus Penicillium chrysogenum was first used successfully to treat an infection caused by a bacterium. Use of penicilin revolutionised the treatment of pathogenic disease. Many formally fatal diseases caused by bacteria became treatable.





Cephalosporins also contain the beta lactam ring. The original fungus found to produce the compounds was a Cephalosporium, hence the name. As with penicillin, the cephalosporin antibiotics have a number of disadvantages. Industrial modification of the active ingredients has reduced these problems.





The only broadly useful antifungal agent from fungi is griseofulvin. The original source was Penicillium griseofulvin. Griseofulvin is fungistatic, rather than fungicidal. It is used for the treatment of dermatophytes, as it accumulates in the hair and skin following topical application

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